Interesting podcast

About weight gain/loss factors. It's rather long but very interesting! They talk about the concept of an adipostat, essentially an internal mechanism that regulates fat loss/gain (kind of like how a thermostat regulates heat), and discuss various factors that impact the set point of the adipostat. They go into some detail on low-carb diets but it's not just that. There isn't always just one thing, is there? They talk about omega-3s versus omega -6s, about the possible role of gut flora and so much more. 

http://thehealthyskeptic.org/podcasts/THSpodcast_episode1.mp3

Highly recommend listening to this, even if you're not struggling with weight loss issues.